- What does folate do for the body?
- Can high folate cause neuropathy?
- What medical conditions cause high folate levels?
- How can you tell the difference between folate and b12 deficiency?
- What does it mean if your folate levels are high?
- Does high folate level mean cancer?
- Is it bad to have too much folate?
- Does folic acid stay in your system?
- Is folic acid toxic in high doses?
- What are the symptoms of high folic acid?
- What is a good folate level?
- Can high folate levels mask b12 deficiency?
- What is the normal range for folate in blood test?
- What is the difference between b12 and folate?
What does folate do for the body?
Folate is a B-vitamin that is naturally present in many foods.
Your body needs folate to make DNA and other genetic material.
Your body also needs folate for your cells to divide.
A form of folate, called folic acid, is used in fortified foods and most dietary supplements..
Can high folate cause neuropathy?
However, previous studies have found evidence that excess folate intake could potentially worsen associated neurological deficits, including peripheral neuropathy, in older adults.
What medical conditions cause high folate levels?
There are several other medical conditions that may increase folic acid needs including anyone taking medications for epilepsy, Rheumatoid arthritis, lupus, psoriasis, asthma, and inflammatory bowel disease; anyone with kidney disease who is on dialysis; anyone with liver, sickle cell, or celiac diseases.
How can you tell the difference between folate and b12 deficiency?
Additional testing with homocysteine and MMA determinations may help distinguish between B12 and folate deficiency states. In folate deficiency, homocysteine levels are elevated and MMA levels are normal. In vitamin B12 deficiency, both homocysteine levels and MMA levels are elevated.
What does it mean if your folate levels are high?
High levels of folate in the blood may mean that you eat a diet rich in folate or folic acid, take vitamins, or take folic acid pills. Consuming more folate than the body needs does not cause problems. High folate levels can also mean a vitamin B12 deficiency.
Does high folate level mean cancer?
“Today it’s worrisome that taking extra folate over the long term might lead to more DNA methylation, which then might lead to extra diseases including potentially an increased chance of developing cancer and other diseases of aging,” Issa said.
Is it bad to have too much folate?
You can’t get too much from foods that naturally contain folate. You should not get more than 1,000 micrograms of folic acid a day, unless your doctor prescribes a higher amount. Too much folic acid can hide signs that you lack vitamin B12, which can cause nerve damage.
Does folic acid stay in your system?
Folic acid is water-soluble. Leftover amounts of the vitamin leave the body through the urine. That means your body does not store folic acid. You need to get a regular supply of the vitamin through the foods you eat or through supplements.
Is folic acid toxic in high doses?
A toxic dose has not been established, but folic acid is generally nontoxic. Intakes more than 5000 mcg/day mask pernicious anemia.
What are the symptoms of high folic acid?
Although doses up to 5 mg daily have been safely used in some research, doses of folic acid greater than 1 mg daily might cause abdominal cramps, diarrhea, rash, sleep disorders, irritability, confusion, nausea, stomach upset, behavior changes, skin reactions, seizures, gas, excitability, and other side effects.
What is a good folate level?
If the test is done on your blood plasma, a normal range for folate is 2 to 10 ng/mL. If the test is done on red blood cells, a normal range is 140 to 960 ng/mL. If your folate results are low, it may mean you have: A diet that doesn’t provide enough folate.
Can high folate levels mask b12 deficiency?
The extra folic acid may be masking vitamin B-12 deficiency in people 60 and older, warns one of the nation’s leading researchers on the B vitamins. Folic acid and vitamin B-12 are needed to produce sufficient numbers of normal red blood cells, and a shortage of either can cause anemia.
What is the normal range for folate in blood test?
The normal range is 2.7 to 17.0 nanograms per milliliter (ng/mL) or 6.12 to 38.52 nanomoles per liter (nmol/L). Normal value ranges may vary slightly among different labs.
What is the difference between b12 and folate?
Vitamin B12, also called cobalamin, is found in foods from animals, such as red meat, fish, poultry, milk, yogurt, and eggs. Folate (Vitamin B9) refers to a natural occurring form of the vitamin, whereas folic acid refers to the supplement added to foods and drinks.